FOR YOUR PATIENTS WITH
CKD-ASSOCIATED PRURITUS ON HD
TREAT THE ITCH
WITH PrKORSUVA®
PrKORSUVA® (difelikefalin) is indicated for the treatment of moderate-to-severe pruritus associated with chronic kidney disease (CKD) in adult patients on hemodialysis (HD).1
CKD-associated pruritis – an itch that can be intense and generalized and may reduce quality of life (QoL)2
A common, distressing, underrecognized, and underreported condition2,3

Based on an international study in 21 countries from 2009-2018, results from patients in Canada suggested
40% of Canadian patients
treated with in-centre HD reported being at least moderately bothered by itchy skin4*

69% of medical units
underestimated the prevalence of pruritus3
Based on an international study in 17 countries from 1996-2015, data suggested
17% of patients
nearly always or always bothered by itchy skin had not reported their symptoms to any healthcare provider3* Dialysis Outcomes and Practice Patterns Study (DOPPS): a prospective cohort study of 23,264 hemodialysis patients in 21 countries, including 1,316 Canadian patients.
Click here for additional information and for a link to the Product Monograph discussing:
- Relevant warnings and precautions regarding cardiac failure and atrial fibrillation; driving and operating machinery; hyperkalemia; dizziness and somnolence; gait disturbances, including falls; mental status changes; patients with impaired blood-brain barrier; pregnant women; breastfeeding; and geriatrics (≥65 years of age).
- Conditions of clinical use, adverse reactions, drug interactions, and dosing instructions.