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FOR YOUR PATIENTS WITH

CKD-ASSOCIATED PRURITUS ON HD

TREAT THE ITCH
WITH PrKORSUVA®

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PrKORSUVA® (difelikefalin) is indicated for the treatment of moderate-to-severe pruritus associated with chronic kidney disease (CKD) in adult patients on hemodialysis (HD).1
CKD-associated pruritis – an itch that can be intense and generalized and may reduce quality of life (QoL)2

A common, distressing, underrecognized, and underreported condition2,3

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Based on an international study in 21 countries from 2009-2018, results from patients in Canada suggested

40% of Canadian patients

treated with in-centre HD reported being at least moderately bothered by itchy skin4*

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69% of medical units

underestimated the prevalence of pruritus3

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Based on an international study in 17 countries from 1996-2015, data suggested

17% of patients

nearly always or always bothered by itchy skin had not reported their symptoms to any healthcare provider3

* Dialysis Outcomes and Practice Patterns Study (DOPPS): a prospective cohort study of 23,264 hemodialysis patients in 21 countries, including 1,316 Canadian patients.

Click here for additional information and for a link to the Product Monograph discussing:
  • Relevant warnings and precautions regarding cardiac failure and atrial fibrillation; driving and operating machinery; hyperkalemia; dizziness and somnolence; gait disturbances, including falls; mental status changes; patients with impaired blood-brain barrier; pregnant women; breastfeeding; and geriatrics (≥65 years of age).
  • Conditions of clinical use, adverse reactions, drug interactions, and dosing instructions.

Mechanism of action

Efficacy data

Dosing and administration

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